Friday, November 30, 2007

(BT05113) CELL BIOLOGY

Unit I: Cell structure and function
Discovery of cells; Basic properties of cells; Cell theory; Cell complexity; Different
classes of cells; Prokaryotic & Eukaryotic system, Prokaryotic & Eukaryotic cells;
Unit II: Chemistry of the cell
Importance of carbon and water; Plasma membrane- structure and function; Cytoplasm
& Cytoskeleton; Microtubules, microfilaments & intermediate filaments.
Unit III: Intracellular Compartments
Structure and functions of Nucleus, Endoplasmic Reticulum, Golgi Complex, Lysosomes,
Peroxisomes, Chloroplast & Mitochondria. Protein Glycosylation, Sorting
and Transport.
Unit IV: Transport across Cell Membranes
Passive and Active Transport, Permeases, Na+/K+ Pump, ATPase pumps, Lysosomal
& Vacuolar membrane ATP dependent Proton Pumps, Co-Transport Symport,
Antiport, Transport into Prokaryotic Cells, Endocytosis and Exocytosis.
Unit V: Cell division
Overview of the Cell Cycle, Interphase, Mitosis, Meiosis and Cytokinesis. Animal
Cell & Yeast Cell Division, Cell Cycle Control & Checkpoints.
Unit VI: Cell differentiation
General Characteristics of Cell Differentiation, Historical events in Cell differentiation,
Cytoplasmic determinants, Nucleoplasmic Interactions; Stem Cell differentiation
and its Biological Importance.
Unit VII: Receptors
Cytosolic, Nuclear & Membrane bound receptors, Examples and types of receptors;
Chemo receptors of Bacteria (Attractants & Repellents)
Unit VIII: Signal Transduction
Concept of Secondary messengers, cAMP, cGMP, Protein Kinases, G Proteins,
Steroid / Peptide hormone regulation & Tissue specific regulation.
TEXT BOOKS:
1) The Cell by Cooper.
2) Cell and Molecular biology – De Robertis and De Robertis (1998) Waverly
Pvt. Ltd.
References:
1) Cell & Molecular Biology by Gerald Karp (2nd Ed.) Wiley publishers.
2) The World of the cell by Becker, Reece, Poenie (3rd edition) Benjamin
Publishers.
3) Molecular Biology of the cell by Bruce Alberts.
4) The biochemistry of Cell Signalling-Ernst J.M.Helmreich. Oxford Press.
5) The world of Cell. 5th edition- Becker, Kleinsmith, Harden,-Pearson
Publishers.
6) Cell & Molecular Biology by Phillip Sheeler and Donald E.Blanchi 3rd edition
John Wiley &sons

No comments: