Friday, November 30, 2007

(BT05080) BIOCHEMISTRY

Unit I: Carbohydrate Structure & Function
Structure and properties of Mono, Di, Oligo & polysaccharides, complex carbohydrates,
Confirmation of pyranose & furanose ring, glycosidic bond, Glycogen, starch & dextran;
as mobilizable stores of glucose. cellulose, glycoproteins, glycosaminoglycans & lectins;
structure and function.
UNIT II: Carbohydrate Metabolism
Glycolysis, Glucogenesis, Glycogenolysis, Gluconeogenesis, ED Pathway, Pentoses
phosphate shunt & TCA cycle
UNIT III: Bioenergetics
Respiratory chain, Aerobic and anaerobic respiration; Fermentation.
UNIT IV: Proteins & Amino Acids Metabolism -I
Nitrogen Balance, Amino acids as building blocks of proteins; Protein structure, folding &
function, N2 Cycle, reductive amination & transamination &Urea cycle.
UNIT V: Proteins & Amino Acids Metabolism -II
Synthesis of amino acids - Glutamate pathway; Serine pathway; shikimate pathway for
the production of aromatic amino acids.
Unit VI: Lipids & Their Metabolism
Classifications, Structures and roles of fatty acids; fatty acid breakdown; fatty acid synthesis;
synthesis and metabolism of triglycerols, cholesterol structure and function. Lipoproteins
– classification & function.
UNIT VII: Intermediary Metabolism
Interconnection of pathways & metabolic regulation
UNIT VIII: Photosynthesis
Bacterial & Plant photosynthesis; oxygenic and anoxygenic photosynthesis; chlorophyll
as trapper of solar energy, photosynthetic reaction centres, Hill reaction, PS I & PS II,
Photophosphorylation - cyclic & non-cyclic; Dark reaction & CO2 fixation.
TEXT BOOKS:
1. Lehninger A.L, Nelson O.’L, M.M. Cox, Principles of Biochemistry, CBS
Publications, 1993. ,
2. Fundamentals of Biochemistry J.L. Jain S. Chand Publishers
REFERENCES:
1. Voet D, Voet J. G, Biochemistry, Second Edition, John C Wiley and Sons,
1994.
2. Stryer L, Biochemistry, Fourth edition, 1994.
3. Biochemistry by K. Mathews, K.E. Van Holde, Kevin G Ahern, Pearson education.
4. Protein’s Structure and function. Daviel Whitford John Wiley Publications.
5. Biochemistry by cristopher K.Mathews, K.E.Van Holde, Pearsons education

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