(BT05079) BIO CHEMICAL THERMODYNAMICS

UNIT I: BASIC CONCEPTS IN ENGINEERING THERMODYNAMICS
First and Second law of thermodynamics; Calculation of Work, energy and property
changes in reversible processes, Thermodynamics of flow processes; Power
cycles and refrigeration cycles
UNIT II: THERMODYNAMIC PROPERTIES OF FLUIDS-I
Volumetric properties of gases exhibiting non-ideal behaviour; Residual properties
UNIT III: THERMODYNAMIC PROPERTIES OF FLUIDS-II
Estimation of thermodynamic properties using equations of state; maxwell relationships
and their applications; Calculation of flow processes based on actual property
changes
UNIT IV: SOLUTION THERMODYNAMICS
Partial molar properties; concepts of chemical potential and fugacity Ideal non ideal
solutions; Gibbs Duhem equation; Excess properties of mixtures; Activity Coefficient
- composition models
UNIT V: PHASE EQUILIBRIA
Criteria for phase equilibria; Vapour-liquid equilibrium calculations for binary mixtures,
liquid -Liquid equilibria and Solid-liquid equilibria
UNIT VI: CHEMICAL REACTION EQUILIBRIA
Equilibrium criteria for homogeneous chemical reactions; Evaluation of equilibrium
constant and effect of pressure and temperature on equilibrium constant; Calculation
of equilibrium conversions and yields for single and multiple chemical reactions
UNIT VII: BIOCHEMICAL THERM0DYNAMICS-I
Energetics of Metabolic Pathways; Energy Coupling (ATP & NADH); Stoichiometry
and energetic analysis of Cell Growth and Product Formation- elemental Balances,
Degree of reduction concepts; available -electron balances; yield coefficients;
UNIT VIII: BIOCHEMICAL THERM0DYNAMICS-II
Oxygen consumption and heat evolution in aerobic cultures; thermodynamic efficiency
of growth
TEXT BOOKS :
1. J M.Smith,H.C.Van Ness and M.M.Abbott. Introduction to Chemical Engineering
Thermodynamics McGraw Hill
2. J.A. Roels, Kinetics and Energetics in Biotechnology, Elsevier, 1983